You may have heard by now that it is a great idea to enjoy a glass – or two at most – of delicious, satisfying red wine. In fact, doing so regularly may add a little more zest to your life and keep your heart healthy.
This knowledge came from an initial study in 1992, when the term French Paradox was introduced after researchers showed in an epidemiological study that the French, despite higher incidence of smoking, less exercise and a diet relatively higher in fatty foods than Americans, have a lower incidence of heart disease, heart attacks and strokes. The researchers correlated this health paradox to the French love of red wine.
French red wine grapes contain two main constituents shown to be of significant antioxidant value: polyphenols (flavonoids) and resveratrol. Animal studies of red wine polyphenols have demonstrated effects in cardioprotection, supporting healthy cholesterol levels, vision improvement and general free-radical scavenging.
Resveratrol is produced by grapes to protect against fungal infection. It has been shown in studies to exert potent cardioprotection by inhibiting LDL oxidation and reducing platelet aggregation. In a rat model study, researchers found that resveratrol had a dramatic effect against ischemia-reperfusion-induced arrhythmias. Resveratrol reduced both the incidence and duration of ventricular dysrhythmias, including ventricular tachycardia and ventricular fibrillation. What this means is that is supports healthy heart function.
A significant study, published in 2006 in the journal Nature, demonstrated that obese mice fed red wine extract (resveratrol) were in better health and lived longer than obese mice that were not fed the red wine extract. In the supplement group, deaths dropped 31%, compared to the control group. Study authors also concluded that the red wine extract group of mice lived longer than what they normally should have given their obesity.
David Sinclair, co-author of the study, told Newsweek, “At the genetic level, we saw alterations in all the known longevity pathways that we looked at. It would appear this molecule triggers our natural genetic defenses against aging. That’s probably why resveratrol is such a potent molecule. It’s no mere antioxidant.”
In addition, Sinclair said that his team saw benefits in the supplement group that are associated with healthy longevity, specifically lower insulin, body temperature and blood sugar.
References:
Rao AV, et al. Bioabsorption and invivo antioxidant properties of the grape extract BioVin® polyphenols: a human intervention study. Journal of Medicinal Food 200; 3:15-22.
Renaud S, et al. Wine, alcohol, platelets and the French paradox for coronary heart disease. The Lancet 1992; 339:1523-6.
Baur J, et al. Resveratrol improves health and survival of mice on a high calorie diet. Nature. 2006; 444:337-342
For more information click on the links to see some articles about resveratrol:
Mayo Clinic: “Red wine and resveratrol: Good for your heart?”
60 Minutes: “Fountain of Youth in A Wine Rx?”
Total Health for Longevity: “Resveratrol: Unique Nutrient for Extending Health Into Old Age”