Posts Tagged ‘efficacy’

Synergistic Effects of D-Chiro-Inositol and Manganese in Diabetic-Induced Rats

Tuesday, March 2nd, 2010

Cyvex’ Chirositol™ study “Synergistic Effects of D-Chiro-Inositol and Manganese on Blood Glucose and Body Weight of Streptozotocin-Induced Diabetic Rats” has been published in the international peer review journal Current Bioactive Compounds.

The purpose of the study was to investigate the efficacy of prolonged oral administration of Chirositol™ >95% D-Chiro-Inositol (DCI) alone and in combination with manganese sulfate on reducing blood glucose in streptozotocin (STZ)-induced diabetic rats.  The known benefits of DCI have been suggested in sugar metabolism, polycystic ovarian syndrome (PCOS), and weight loss.

In the study, Chirositol™ and manganese sulfate were administered orally, singly, and in combination to diabetic-induced rats for 21 days.  Oral Chirositol™ administration to diabetic rats for 12 days decreased their blood glucose by 23% as compared to controls.  Oral Chirositol™   and manganese sulfate administration to diabetic rats for 12 days decreased their blood glucose by 40% as compared to controls.  Experimental groups did not display hypoglycemia either clinically or by blood glucose levels and/or demonstrated any other adverse reactions.  Of further interest, body weights of both female and male rats administered Chirositol™ and manganese sulfate were reduced, with females 25% compared to controls and males 21% compared to controls over the 21-day period.

With over 30 plus published scientific studies in peer review journals since 1979 providing insight in metabolic disorders, mechanism of action, and established safety, Chirositol™ and Chirositol™ M (containing manganese sulfate) contribute their role in the overall understanding of diabetes mellitus.

For more information on Chirositol™ visit www.chirositol.com or if you would like to view the study, please contact sales@cyvex.com

Branded vs. Generic Ingredients

Tuesday, December 8th, 2009

You may believe that there’s no difference between a generic ingredient and a brand name ingredient, except the fancy name.

Generics, or “no frills” products, indeed have their place in industry and in retail.  However, there are many key factors why, when it comes to many ingredients, notably specialty ones, the proprietary branded ingredients make smart investment sense.

Branded ingredients are often what the finished product manufacturer touts as its product’s identity, either in full or in part.  So the branded ingredient needs to be one that is easily read and grasped by the consumer as the brand marketer is counting on making a memorable first impression.

Branding starts in the supplier’s research and development, along with cultivating relationships with growers and processors responsible for producing superior quality and pure product. Often, a well-researched and proven-effective proprietary processing technique that enhances the biological value of the ingredient versus its generic counterpart is a significant part.

Once an ingredient and the facility that manufactures it are assured of exceptional quality and the research of its safety and efficacy are likewise validated, it is taken to a marketing think tank to create a brand around it. This includes a name that reflects the nature of the ingredient and that also speaks to a core consumer that will find it valuable. A logo is also developed, and paperwork is filed for trademark protection.

Crafting a valuable branded ingredient is, therefore, an investment. Reputable branded ingredients have everything: the quality research, the quality production, the characteristic distinctions, and the marketing savvy.

When it comes to specialty ingredients such as antioxidants, the power of branded ingredients makes the best sense for long-term product success!